| LncRNA | MiRNA | Gene | Gene name | Pathway Name | Description | Title | Disease/Tissue | Journal | PubMed ID |
| H19 | miR-675 | PTEN | PTEN；10q23del；BZS；CWS1；DEC；GLM2；MHAM；MMAC1；PTEN1；TEP1 | details
p53 signaling pathway；Inositol phosphate metabolism；Prostate cancer；Phosphatidylinositol signaling system；mTOR signaling pathway；PI3K-Akt signaling pathway；Focal adhesion；Tight junction；Hepatitis B；Pathways in cancer；Melanoma；Endometrial cancer；Glioma；Small cell lung cancer
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LncRNA H19-derived microRNA (miR-675) are overexpressed in neointima of balloon-injured artery. We further validated that PTEN is the target gene of miR-675 as demonstrated by luciferase assay. Finally, the results of the rescue experiment indicated that LncRNA H19 promoted the proliferation of T/G HA-VSMC in a miR-675-dependent manner.
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Long noncoding RNA H19-derived miR-675 aggravates restenosis by targeting PTEN
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Vascular Smooth Muscle Cells | Biochem Biophys Res Commun | 28063931 |