| LncRNA | MiRNA | Gene | Gene name | Pathway Name | Description | Title | Disease/Tissue | Journal | PubMed ID |
| MALAT1 | miR-124 | JAG1 | JAG1；AGS；AHD；AWS；CD339；HJ1；JAGL1 | details
Notch signaling pathway
|
details
In the present study, lncRNA-MALAT1 was specifically upregulated in tongue cancer cell lines and overexpression promoted tongue cancer cell growth by targeting miR-124. Knockdown of MALAT1 suppressed the growth and invasion of human tongue cancer cells and inhibited metastasis in vitro and in vivo. In addition, miR-124-dependent jagged1 (JAG1) regulation was required for MALAT1-induced tongue cancer cell growth. Our data revealed that MALAT1 inhibited tongue cancer cell growth and metastasis through miR-124-dependent JAG1 regulation
|
details
Long non-coding RNA MALAT1 interacts with miR-124 and modulates tongue cancer growth by targeting JAG1
|
Tongue Cancer | Oncol Rep | 28260102 |