LncRNA | MiRNA | Gene | Gene name | Pathway Name | Description | Title | Disease/Tissue | Journal | PubMed ID |
H19 | miR-29b-3p | TGFB1 | TGFB1;CED;DPD1;LAP;TGFB;TGFbeta | details
Hippo signaling pathway;MAPK signaling pathway;Cytokine-cytokine receptor interaction;Cell cycle;Endocytosis;TGF-beta signaling pathway;Renal cell carcinoma;Hypertrophic cardiomyopathy (HCM);Chronic myeloid leukemia;Toxoplasmosis;Pathways in cancer;Osteoclast differentiation;HTLV-I infection;Proteoglycans in cancer;Intestinal immune network for IgA production;Rheumatoid arthritis;Dilated cardiomyopathy;Hepatitis B;Pancreatic cancer;Leishmaniasis;Tuberculosis;Chagas disease (American trypanosomiasis);Colorectal cancer; Malaria
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Furthermore, miR-29b-3p directly suppressed the expression of TGF-β1 and type I collagen, thereby forming a novel regulatory feedback loop between H19 and TGF-β1 to mediate tenogenic differentiation.
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Long noncoding RNA H19 accelerates tenogenic differentiation and promotes tendon healing through targeting miR-29b-3p and activating TGF-β1 signaling
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Tendon Injures | FASEB J | 27895107 |