LncRNA | MiRNA | Gene | Gene name | Pathway Name | Description | Title | Disease/Tissue | Journal | PubMed ID |
XIST | miR-494 | PTEN | PTEN;10q23del;BZS;CWS1;DEC;GLM2;MHAM;MMAC1;PTEN1;TEP1 | details
p53 signaling pathway;Inositol phosphate metabolism;Prostate cancer;Phosphatidylinositol signaling system;mTOR signaling pathway;PI3K-Akt signaling pathway;Focal adhesion;Tight junction;Hepatitis B;Pathways in cancer;Melanoma;Endometrial cancer;Glioma;Small cell lung cancer
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In particular, our results suggested that lncRNA-XIST may act as a competitive endogenous RNA, effectively becoming a sink for miR-494, leading to derepression of its target gene, phosphatase and tensin homolog deleted on chromosome ten (PTEN).
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Long Coding RNA XIST Contributes to Neuronal Apoptosis through the Downregulation of AKT Phosphorylation and Is Negatively Regulated by miR-494 in Rat Spinal Cord Injury
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Rat Spinal Cord Injury | Int J Mol Sci | 28368292 |