LncRNA | MiRNA | Gene | Gene name | Pathway Name | Description | Title | Disease/Tissue | Journal | PubMed ID |
mmu_circRNA_007893 | mmu-miR-485-5p | IL-6 | IL6;BSF2;HGF;HSF;IFNB2;IL-6 | details
NOD-like receptor signaling pathway;Cytokine-cytokine receptor interaction;HIF-1 signaling pathway;PI3K-Akt signaling pathway;Toll-like receptor signaling pathway;Legionellosis;Hypertrophic cardiomyopathy (HCM);African trypanosomiasis;Cytosolic DNA-sensing pathway;Jak-STAT signaling pathway;Hematopoietic cell lineage;Intestinal immune network for IgA production;Transcriptional misregulation in cancer;Influenza A; Herpes simplex infection;Pathways in cancer;Chagas disease (American trypanosomiasis);Graft-versus-host disease;Malaria;Prion diseases;Pertussis;Rheumatoid arthritis;Measles;Salmonella infection;Amoebiasis;Hepatitis B;HTLV-I infection;Tuberculosis
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Furthermore, when overexpression of mmu-miR-485-5p, IL-6 mRNA was markedly decreased. The results demonstrated that CGRP-induced IL-6 mRNA expression was mediated by mmu_circRNA_007893, and mmu_circRNA_007893 functioned as an endogenous mmu-miR-485-5p sponge as part of induction of IL-6 mRNA expression.
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Calcitonin gene?related peptide induces IL?6 expression in RAW264.7 macrophages mediated by mmu_circRNA_007893
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RAW264.7 macrophages | Mol Med Rep | 29039515 |