| LncRNA | MiRNA | Gene | Gene name | Pathway Name | Description | Title | Disease/Tissue | Journal | PubMed ID |
| MALAT1 | miR-224-5p | MMP14 | MMP14；MMP-14；MMP-X1；MT-MMP；MT-MMP 1；MT1-MMP；MT1MMP；MTMMP1；WNCHRS | details
GnRH signaling pathway
|
details
We determined that MALAT1 promotes melanoma cells proliferation, invasion and migration by sponging miR-22. MiR-22 was decreased and acted as a tumor suppressor in melanoma, and MMP14 and Snail were the functional targets of miR-22. Furthermore, MALAT1 could modulate MMP14 and Snail by operating as a competing endogenous RNA (ceRNA) for miR-22.
|
details
Long non-coding RNA MALAT1 acts as a competing endogenous RNA to promote malignant melanoma growth and metastasis by sponging miR-22
|
Malignant Melanoma | Oncotarget | 27564100 |