LncRNA | MiRNA | Gene | Gene name | Pathway Name | Description | Title | Disease/Tissue | Journal | PubMed ID |
NEAT1 | miR-107 | CDK6 | CDK6;MCPH12;PLSTIRE | details
Hepatitis B;Cell cycle;p53 signaling pathway;PI3K-Akt signaling pathway;Measles;Pathways in cancer; Small cell lung cancer;Non-small cell lung cancer;Viral carcinogenesis;Pancreatic cancer;Glioma;Melanoma;Chronic myeloid leukemia
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Furthermore, NEAT1 regulated CDK6 expression in LSCC cells which was mediated by miR-107.
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Long noncoding RNA NEAT1 promotes laryngeal squamous cell cancer through regulating miR-107/CDK6 pathway
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Laryngeal Squamous Cell Cancer | J Exp Clin Cancer Res | 26822763 |
H19 | miR-148a-3p | DNMT1 | DNMT1;ADCADN;AIM;CXXC9;DNMT;HSN1E;MCMT | details
Cysteine and methionine metabolism;Metabolic pathways
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We identified microRNA miR-148a-3p as an inhibitory target for H19. Overexpression of miR-148a-3p reduced LSCC migration, invasion and proliferation cell, while inhibition of miR-148a-3p did the opposite. The inhibition of LSCC progression induced by H19 knockdown required the activity of miR-148a-3p. We also identified DNA methyltransferase enzyme DNMT1 as a target of miR-148a-3p
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Regulation of laryngeal squamous cell cancer progression by the lncRNA H19/miR-148a-3p/DNMT1 axis
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Laryngeal Squamous Cell Cancer | Oncotarget | 26872375 |