KEGG Module

KEGG pathway analysis and metabolic network exploration

KEGG Module Interface

Module Overview

The KEGG module provides comprehensive access to Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway data through an intuitive search interface. This module serves as the central hub for exploring metabolic pathways, biological processes, and functional annotations across insect species.

Key Features

  • 1Select your target insect species from a comprehensive database of available organisms
  • 2Choose from hundreds of KEGG pathways including metabolic, signaling, and disease pathways
  • 3Execute rapid searches to discover genes associated with specific pathways and biological processes

Search Process

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Step 1: Select Species

Choose from available insect species using the searchable dropdown menu. You can search by species name or browse the complete list.

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Step 2: Choose Pathway

Select from hundreds of KEGG pathways including metabolism, signaling, disease, and drug resistance pathways.

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Step 3: Execute Search

Click the search button to quickly find genes associated with your selected pathway in the chosen species.

KEGG Pathway Categories

Metabolism

Carbohydrate, lipid, amino acid, and nucleotide metabolism pathways

Genetic Information Processing

Transcription, translation, replication, and repair pathways

Environmental Information Processing

Signal transduction and membrane transport pathways

Cellular Processes

Cell cycle, apoptosis, and cellular communication pathways

Organismal Systems

Immune, endocrine, and nervous system pathways

Human Diseases

Cancer, neurodegenerative, and metabolic disease pathways

Search Tips for Optimal Results

Species Selection

  • Use the search box to quickly find specific species
  • Select multiple species for comparative analysis
  • Check species availability before pathway selection

Pathway Selection

  • Search pathways by name or KEGG ID
  • Browse categories to discover related pathways
  • Use pathway descriptions to understand functionality

Usage Examples

Example 1: Exploring Glycolysis in Drosophila

  1. Select “Drosophila melanogaster” from the organism dropdown
  2. Search for “glycolysis” in the pathway search box
  3. Select “map00010 - Glycolysis / Gluconeogenesis” pathway
  4. Click “Search Genes” to find all glycolysis-related genes

Example 2: Comparative Pathway Analysis

  1. Select multiple species (e.g., Drosophila, Bombyx, Apis)
  2. Choose a pathway of interest (e.g., “map04010 - MAPK signaling pathway”)
  3. Execute search to compare pathway genes across species
  4. Analyze differences in pathway composition between species

Available Data Types

KEGG Pathways

Metabolic and signaling pathways

Gene Annotations

KEGG and KO identifiers

Gene Lists

Pathway-associated genes

External Links

KEGG database links

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